2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) - Names and Identifiers
Nombre | 2 (1h) - piridina, 3 - cloro - 4 - hidroxi - (9ci)
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Sinónimos | 3-Chloro-2,4-dihydroxypyridine 5-Chloro-4-hydroxy pyridinone-2 3-Chloro-4-hydroxy-2(1H)-pyridinone 3-chloro-2-hydroxypyridin-4(1H)-one 3-chloro-2-hydroxy-1H-pyridin-4-one 3-Chloro-4-hydroxypyridin-2(1H)-one 2(1H)-Pyridinone, 3-chloro-4-hydroxy- 2 (1h) - piridina, 3 - cloro - 4 - hidroxi - (9ci) 3-chloro-4-hydroxy-1,2-dihydropyridin-2-one
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CAS | 103792-81-0
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InChI | InChI=1/C5H4ClNO2/c6-4-3(8)1-2-7-5(4)9/h1-2H,(H2,7,8,9) |
2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) - Physico-chemical Properties
Fórmula Molecular | C5H4ClNO2
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Masa Molar | 145.54 |
Densidad | 1.56 |
Punto de fusión | 310 °C (decomp) |
punto Boling | 283 ºC |
Punto Flash | 125 ºC |
Presión de vapor | 0.00412mmHg at 25°C |
PKa | 4.50±1.00(Predicted) |
Condición de almacenamiento | Temperatura de la habitación |
Índice de refracción | 1.617 |
MDL | MFCD11101041 |
2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) - Introduction
3-Chloro-2, 4-dihydroxypyridine is an organic compound with the chemical formula C5H4ClNO2, often abbreviated as 3-Cl-2,4-DHP. The following is an introduction to some of its properties, uses, methods and safety information:
Naturaleza:
1. Appearance: 3-chloro-2, 4-dihydroxypyridine is a colorless to pale yellow crystalline solid.
2. Melting point: Its melting point is about 228-230 degrees Celsius.
3. Solubility: 3-chlorine -2, 4-dihydroxypyridine has low solubility in water, but it can be dissolved in organic solvents such as alcohol, ether, etc.
Uso:
1. Pesticide: 3-Chloro-2, 4-dihydroxypyridine is a broad-spectrum pesticide that can be used to control pests on a variety of agricultural crops.
2. Medicine: It is also used as a pharmaceutical intermediate and can be used to synthesize other compounds with medicinal value.
Método de preparación:
3-Chloro-2, 4-dihydroxypyridine is mainly prepared by the following methods:
1. Hydroxylation method: it is obtained by reacting 2,4-dihydroxypyridine with cuprous chloride, and then further hydroxylation with silver chloride.
2. Hydroxychlorination method: it is obtained by reacting 2,4-dihydroxypyridine with cuprous chloride under the catalysis of stannous chloride.
3. hydroxylation-chlorination method: by reacting 2,4-dihydroxypyridine with sodium chlorite to obtain an intermediate product, and then reacting with chlorous acid and sodium chloride for hydroxylation.
Información de seguridad:
The following points should be noted when using 3-chloro-2, 4-dihydroxypyridine:
1. Avoid direct contact: gloves and protective glasses should be used when handling 3-chloro-2, 4-dihydroxypyridine to avoid skin and eye irritation or damage.
2. storage note: 3-chlorine -2, 4-dihydroxypyridine should be stored in a dry, cool place, away from fire and oxidant, avoid high temperature and direct sunlight.
3. Toxic effects: 3-chloro-2, 4-dihydroxypyridine has certain toxicity, and long-term exposure or exposure may cause health effects. Relevant safety data should be read carefully before use and chemical safety procedures should be strictly followed.
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