4-Chloro-5H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile

4-Chloro-5H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile - Names and Identifiers

Nombre	4-Chloro-5H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile
Sinónimos	4-Chloro-5H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile 1H-Pyrazolo[3,4-d]pyriMidine-3-carbonitrile, 4-chloro- 1H-Pyrazolo[3,4-d]pyrimidine-3-carbonitrile, 4-chloro-
CAS	1004991-91-6
InChI	InChI=1S/C6H2ClN5/c7-5-4-3(1-8)11-12-6(4)10-2-9-5/h2H,(H,9,10,11,12)

4-Chloro-5H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile - Physico-chemical Properties

Fórmula Molecular	C6H2ClN5
Masa Molar	179.57
Densidad	1.73±0.1 g/cm3(Predicted)
punto Boling	447.1±40.0 °C(Predicted)
PKa	5.59±0.43(Predicted)
Condición de almacenamiento	bajo gas inerte (nitrógeno o argón) a 2-8°C

4-Chloro-5H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile - Introduction

3-Acetonitrile-4-chloro-1H-pyrazolo [3,4-d] pyrimidine is an organic compound with the chemical formula C7H4ClN3. It is a white crystalline solid, soluble in some organic solvents such as chloroform and dichloromethane. The following is a brief description of some of the properties, uses, preparation and safety information of the compound:

Naturaleza:
-Appearance: White crystalline solid
-melting point: about 160-163 ℃
-Solubility: Soluble in chloroform, dichloromethane, slightly soluble in ethanol and ether
-chemical properties: with strong alkaline

Uso:
-3-Acetonitrile-4-chloro-1H-pyrazole [3,4-d] pyrimidine can be used as a pharmaceutical intermediate for the synthesis of some drugs and active molecules.
-It can also be used as a synthetic intermediate for chemicals such as photosensitive dyes, photosensitive materials and polyimides.

Método de preparación:
3-acetonitrile-4-chloro-1H-pyrazole [3,4-d] pyrimidine has many preparation methods, and the common methods include:
-Synthesized by the reaction of p-aminopyrazole and cyanoacetate.
-Synthesized by the condensation reaction of cyanoacetate and 4-chloropyridine.

Información de seguridad:
3-Acetonitrile-4-chloro-1H-pyrazolo [3,4-d] pyrimidine is less toxic, but it should still be used and handled correctly.
-Wear appropriate personal protective equipment such as lab clothes, glasses and gloves when handling the compound.
-Avoid inhaling dust and vapors of the substance, avoid skin contact and eye contact.
-In the storage and handling process to maintain good ventilation conditions, avoid direct sunlight.
-In case of contact with the substance, rinse the affected area immediately with plenty of water and seek medical attention.