5,7-Dichloro-1H-pyrrolo[2,3-c]pyridine - Names and Identifiers
Nombre | 5,7-Dichloro-1H-pyrrolo[2,3-c]pyridine
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Sinónimos | 138235 5,7-Dichloro-6-azaindole 5,7-DICHLORO-6-AZAINDOLE 5,7-dichloro-1H-pyrrolo[2,3-c]pyridine 5,7-Dichloro-1H-pyrrolo[2,3-c]pyridine 1H-Pyrrolo[2,3-c]pyridine, 5,7-dichloro-
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CAS | 1001412-41-4
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EINECS | 200-258-5 |
InChI | InChI=1S/C7H4Cl2N2/c8-5-3-4-1-2-10-6(4)7(9)11-5/h1-3,10H |
5,7-Dichloro-1H-pyrrolo[2,3-c]pyridine - Physico-chemical Properties
Fórmula Molecular | C7H4Cl2N2
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Masa Molar | 187.03 |
Densidad | 1.571 |
punto Boling | 371.6±37.0 °C(Predicted) |
PKa | 12.16±0.40(Predicted) |
Condición de almacenamiento | bajo gas inerte (nitrógeno o argón) a 2-8°C |
5,7-Dichloro-1H-pyrrolo[2,3-c]pyridine - Introduction
Naturaleza:
5,7-Dichloro-1H-pyrrolo [2,3-c] pyridine is a colorless to pale yellow solid, soluble in organic solvents, insoluble in water. It has a melting point of 210-215°C and a boiling point of about 380°C.
Uso:
5,7-Dichloro-1H-pyrrolo [2,3-c] pyridine has a wide range of applications in the field of organic synthesis. It is an effective sulfur dichloride deprotection reagent and can be used to remove protecting groups in alcohols, phenols or ethers. In addition, it can also be used as a nitrogen source in organic synthesis, a carbon source, a synthetic reagent for aromatic compounds, etc.
Método de preparación:
5,7-Dichloro-1H-pyrrolo [2,3-c] pyridine is generally synthesized by chlorination of pyrrolo [2,3-c] pyrrole. First, pyrrolo [2,3-c] pyrrole is reacted with thionyl chloride in a suitable solvent, followed by hydrogenation under basic conditions to obtain the target product.
Información de seguridad:
5,7-Dichloro-1H-pyrrolo [2,3-c] pyridine may be harmful to humans under certain conditions. It may be irritating to the skin, eyes and respiratory system. Wear appropriate personal protective equipment during use or operation to prevent contact and inhalation. At the same time, it should be ensured that the operation is carried out in a well-ventilated place. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
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