IntroductionCAS:80-08-0.80-08-0–NamesandIdentifiersName4-AminophenylsulfoneSynonymsDDSEPORALDap
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CAS:80-08-0.
80-08-0–NamesandIdentifiers
Name4-Aminophenylsulfone
SynonymsDDS
EPORAL
Dapsone
4.4′-DDS
DISULONE
NOVOPHONE
AVLOSULFON
SULFONA-MAE
SULPHADIONE
TIMTEC-BBSBB003168
4-Aminophenylsulfone
P-AMINOPHENYLSULFONE
4.4-Sulfonyldianiline
diaminodiphenylsulfone
P,P’-SULFONYLDIANILINE
4.4-sulphonyldianiline
4-Aminophenylsulphone
BIS(P-AMINOPHENYL)SULFONE
BIS(4-AMINOPHENYL)SULFONE
di(4-aminophenyl)sulphone
4.4′-Diaminodiphenylsulfone
4.4-Diaminodiphenylsulfone
4.4-Diaminodiphenylsulphone
4.4′-DiaminoDiphenylSulfone
4.4′-Diaminodiphenylsulphone
4.4′-DiaminoDiphenylSulphone
4-((4-aminophenyl)sulfonyl)phenylamine
4.4′-Diaminodiphenylsulfoneforsynthesis
FREESAMPLENCV4.4-DIAMINODIPHENYLSULPHONESTD
CAS80-08-0
EINECS201-248-4
InChIInChI=1/C12H10O2S.C7H6N2O5/c13-15(14.11-7-3-1-4-8-11)12-9-5-2-6-10-12;1-4-2-5(8(11)12)3-6(7(4)10)9(13)14/h1-10H;2-3.10H,1H3
InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N
MolecularFormulaC12H12N2O2S
MolarMass248.3
Density1.2701(roughestimate)
MeltingPoint175-177°C(lit.)
BolingPoint511.7±35.0°C(Predicted)
WaterSolubility<0.1g/100mLat20ºC
Solubility0.38g/l
VaporPresure0.004Paat25℃
AppearanceCrystallinePowder
ColorWhitetobeige
Merck14.2822
BRN788055
pKapKb13.0(at25℃)
PH5.5-7.5(H2O,20℃)(saturatedaqueoussolution)
StorageCondition2-8°C
StabilityStable.Combustible.Incompatiblewithstrongoxidizingagents.
RefractiveIndex1.5950(estimate)
PhysicalandChemicalPropertiesMeltingpoint173-178°C
water-soluble<0.1g/100mLat20°C
UseThedrugofchoiceforthetreatmentofleprosy,canalsobecombinedwithotheranti-leprosydrugs
HazardSymbolsXn–Harmful
RiskCodes22–Harmfulifswallowed
SafetyDescription22–Donotbreathedust.
UNIDs3249
WGKGermany1
RTECSBY8925000
TSCAYes
HSCode29309070
HazardClass6.1(b)
PackingGroupIII
ToxicityLD50orallyinRabbit:1000mg/kgLD50dermalRabbit>4000mg/kg
This product is 4.4‘-sulfonylbis-aniline.Calculated as the dried product,the content of C12H12N202S shall no tbe less than 99.0%.
This product is white or off-white crystalline or crystalline powder;Odorless.
This product is soluble in acetone,dissolved in methanol,slightly soluble in ethanol,almost insoluble in water;Dissolved in dilute hydrochloric acid.
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