Fmoc-L-alpha-phenylglycine

Fmoc-L-alpha-phenylglycine - Names and Identifiers

Nombre	Fmoc-L-alpha-phenylglycine
Sinónimos	Fmoc-Phg-OH Fmoc-L-phenylglycine FMoc-(S)-phenylglycine Fmoc-L-alpha-phenylglycine (S)-Fmoc-2-aminophenylacetic acid FMoc-Phg-OH FMoc-L-phenylglycine N-Fmoc-L-2-phenylglycineFmoc-Phg-OH [(9H-Fluoren-9-ylmethoxycarbonylamino)]phenylacetic acid (3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}phenyl)acetic acid (2R)-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)ethanoic acid (2S)-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)ethanoic acid (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-phenylacetic acid
CAS	102410-65-1
EINECS	1533716-785-6
InChI	InChI=1/C23H19NO4/c25-22(26)13-15-6-5-7-16(12-15)24-23(27)28-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21H,13-14H2,(H,24,27)(H,25,26)

Fmoc-L-alpha-phenylglycine - Physico-chemical Properties

Fórmula Molecular	C23H19NO4
Masa Molar	373.4
Densidad	1.299±0.06 g/cm3(Predicted)
Punto de fusión	175-180°C
punto Boling	606.3±50.0 °C(Predicted)
Rotación específica (alfa)	81 º (c=1% in DMF)
Punto Flash	291.103°C
Solubilidad	soluble in Methanol
Presión de vapor	0mmHg at 25°C
Apariencia	Cristal blanco
color	White to Almost white
BRN	5309005
PKa	3.39±0.10(Predicted)
Condición de almacenamiento	2-8°C
Índice de refracción	81 ° (C=1, DMF)
MDL	MFCD00155632

Fmoc-L-alpha-phenylglycine - Risk and Safety

Descripción de seguridad	S22 - No inhalar polvo. S24 / 25 - evite el contacto con la piel y los ojos.
WGK Alemania	3
FLUKA BRAND F CODES	10
Número de aranceles	2924 29 70
Clase de peligro	IRRITANT

Fmoc-L-alpha-phenylglycine - Introduction

Fmoc-L-Phenylglycine is a compound with the chemical formula C28H22N2O5 and a molecular weight of 470.49g/mol. It is an organic amine acid derivative and has important application value.

Fmoc-L-Phenylglycine is commonly used in solid-phase synthesis as part of a synthetic polypeptide chain. It can be synthesized by a solid phase amino acid synthesis method. Solid phase synthesis is a commonly used method of peptide synthesis, in which the amino acids are sequentially fixed on the solid phase material, and the chemical reaction is repeated to construct the polypeptide chain step by step. Fmoc-L-phenylglycine is one of the selective protecting groups (protective group), which can protect the reactivity of the amino group during the synthesis.

For safety information, Fmoc-L-phenylglycine should be stored under dry, dark, low temperature conditions. During operation, attention should be paid to avoid contact with skin and eyes, and good laboratory operating habits and personal protective measures should be maintained. If inhaled, ingested, or in contact with skin, consult a doctor and bring the appropriate Chemical Safety Data Sheet (CSDS).

To sum up, Fmoc-L-phenylglycine is an organic amine acid derivative commonly used in solid-phase synthesis, which has important application value. In chemical synthesis, attention should be paid to safe use and correct operating procedures should be followed.