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mPEG-GA (metoxipolietilenglicol-glutarato) – enfoque en derivados de PEG

Tiempo: Popularidad:0tiempos

mPEG-GA (methoxy polyethylene glycol-glutarate) is a linear monofunctional PEG acid reagent. There is a C4 fatty ester bond hidden between the PEG and COOH groups. This structure enables PEG-glutarate to react with amino groups and peptide coupling agents (such as NHS and DCC, EDC), thus exerting infinite potential in scientific research experiments.

mPEG-GA has multiple roles in chemical synthesis. First, due to its unique molecular structure, mPEG-GA can be used as a non-ionic, non-polar, lipophilic molecular linker to connect active molecules to proteins, antibodies, peptides and other biomolecules. Secondly, the synthesis of mPEG-GA is achieved by forming an amide bond between the amino group of glycine and the hydroxyl group of mPEG. This connection method combines the lipophilicity of mPEG and the hydrophilicity and biocompatibility of glycine, making it highly valuable in biomedical applications.

In addition, mPEG-GA can also be used as a bioimaging agent and immunoassay reagent to improve the sensitivity and specificity of detection. At the same time, the structural design of mPEG-GA can enhance the stability of drugs, avoid premature metabolism and degradation of drugs in the body, and improve the solubility and bioavailability of drugs. In addition, mPEG-GA can also be used as a drug carrier to deliver the anti-inflammatory and anti-tumor active ingredients of drugs and improve the anti-inflammatory and anti-tumor effects of drugs.

In general, mPEG-GA is a chemical reagent with wide application value, which provides new possibilities for research and development in the biomedical field.


【Product Information】

Molecular weight: 1k, 2k, 3.4k, 4k, 5k, 10k, 20k, 30k, 40k (customizable)

Quality control: 95%+

Storage conditions: -20°C, away from light and moisture

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